Characterization of Monocytes-targeted Nanocarriers Biodistribution in Leukocytes in ex-vivo and in-vivo Models

AimsOn intravenous administration, unprotected nanocarriers are rapidly captured by the mononuclear phagocytic system (MPS). This has been exploited for passive targeting of nanoparticulate drug delivery systems for depleting circulating monocytes and macrophages for the treatment of various disorde...

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Bibliographic Details
Main Authors: Einat Cohen-Sela, Michael Chorny, Dikla Gutman, Sivan Komemi, Nickolay Koroukhov, Gershon Golomb
Format: Article
Language:English
Published: Tsinghua University Press 2010-06-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.5101/nbe.v2i2.p91-99