Optimizing the Expression of Human Dopamine Receptors in <i>Escherichia coli</i>

Optimizing the Expression of Human Dopamine Receptors in <i>Escherichia coli</i>

The human dopamine receptors D<sub>2S</sub> and D<sub>3</sub> belong to the group of G protein-coupled receptors (GPCRs) and are important drug targets. Structural analyses and development of new receptor subtype specific drugs have been impeded by low expression yields or re...

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Bibliographic Details
Main Authors: Vanessa Boritzki, Harald Hübner, Anni Allikalt, Peter Gmeiner, Birgitta M. Wöhrl
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
human dopamine receptors
expression in <i>E. coli</i>
GPCR
protein engineering
FACS
radioligand binding
Online Access:https://www.mdpi.com/1422-0067/22/16/8647

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https://www.mdpi.com/1422-0067/22/16/8647

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