Sex hormones influence survival of patients with metastatic urothelial carcinoma undergoing immune checkpoint therapy

Sex hormones influence survival of patients with metastatic urothelial carcinoma undergoing immune checkpoint therapy

Abstract Introduction Clinical trials investigating efficacy of immune checkpoint inhibitors (ICI) revealed sex-specific divergent outcomes in urothelial cancer (UC), suggesting that sex hormones might play an important role in gender-specific dimorphisms of response upon ICI. However, further clini...

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Bibliographic Details
Main Authors: Andrea Katharina Lindner, Felizian Lackner, Piotr Tymoszuk, Dominik Andreas Barth, Andreas Seeber, Florian Kocher, Bettina Toth, Margarethe Hochleitner, Martin Pichler, Renate Pichler
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Biology of Sex Differences
Subjects:
Metastatic urothelial carcinoma
Immunotherapy
Overall survival
Sex hormones
Gonadotropins
Prognostic
Online Access:https://doi.org/10.1186/s13293-023-00522-x

Internet

https://doi.org/10.1186/s13293-023-00522-x

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