Bhlhe40 deficiency attenuates LPS-induced acute lung injury through preventing macrophage pyroptosis

Abstract Background Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) as common life-threatening lung diseases with high mortality rates are mostly associated with acute and severe inflammation in lungs. Recently, increasing evidence supports activated infl...

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Bibliographic Details
Main Authors: Xingxing Hu, Menglin Zou, Weishuai Zheng, Minghui Zhu, Qinhui Hou, Han Gao, Xin Zhang, Yuan Liu, Zhenshun Cheng
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-024-02740-2