Increased Presence of Circulating Cell-Free, Fragmented, Host DNA in Pigs Infected with Virulent African Swine Fever Virus

Increased Presence of Circulating Cell-Free, Fragmented, Host DNA in Pigs Infected with Virulent African Swine Fever Virus

African swine fever virus (ASFV) causes severe hemorrhagic disease in domestic pigs and wild boar, often with high case fatality rates. The virus replicates in the circulating cells of the monocyte–macrophage lineage and within lymphoid tissues. The infection leads to high fever and a variety of cli...

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Bibliographic Details
Main Authors: Ann Sofie Olesen, Louise Lohse, Camille Melissa Johnston, Thomas Bruun Rasmussen, Anette Bøtner, Graham J. Belsham
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
African swine fever virus
cell-free DNA
apoptosis
mitochondrial DNA
biomarker
Online Access:https://www.mdpi.com/1999-4915/15/10/2133

Internet

https://www.mdpi.com/1999-4915/15/10/2133

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