Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4

While RNA interference is conserved across species, small RNA pathways are very diverse. In this study, Gutbrod et al. find that non-canonical roles of Dicer in genome stability are in fact deeply conserved from yeast to humans.

Bibliographic Details
Main Authors: M. J. Gutbrod, B. Roche, J. I. Steinberg, A. A. Lakhani, K. Chang, A. J. Schorn, R. A. Martienssen
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28554-8