Preparation, biological characterization and preliminary human imaging studies of 68Ga-DOTA-IBA

Preparation, biological characterization and preliminary human imaging studies of 68Ga-DOTA-IBA

PurposeIn this study, DOTA-IBA was radiolabeled with 68Ga and we determined the optimum labelling conditions and assessed the biological properties of 68Ga-DOTA-IBA. We investigated the biodistribution of 68Ga-DOTA-IBA in normal animals and undertook PET/CT imaging in humans. Finally, we explored th...

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Bibliographic Details
Main Authors: Yingwei Wang, Qixin Wang, Zan Chen, Jian Yang, Hanxiang Liu, Dengsai Peng, Lei Lei, Lin Liu, Li Wang, Naiguo Xing, Lin Qiu, Yue Feng, Yue Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
DOTA-IBA
68 Ga
PET/CT
99m Tc-MDP
SPECT
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1027792/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1027792/full

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