Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model

Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model

ObjectiveThis study aims to investigate the effects of ankle joint mobilization (AJM) on mechanical hyperalgesia and peripheral and central inflammatory biomarkers after intraplantar (i.pl.) Complete Freund’s Adjuvant (CFA)-induced inflammation.MethodsMale Swiss mice were randomly assigned to 3 grou...

Full description

Bibliographic Details
Main Authors: Carlos Minoru Omura, Daniela Dero Lüdtke, Verônica Vargas Horewicz, Paula Franson Fernandes, Taynah de Oliveira Galassi, Afonso Shiguemi Inoue Salgado, Juliete Palandi, Heloiza dos Santos Baldança, Edsel B. Bittencourt, Josiel Mileno Mack, Lynsey A. Seim, Daniel Fernandes Martins, Franciane Bobinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Physiology
Subjects:
joint mobilization
manual therapy
neuroimmunomodulation
inflammatory cytokines
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.816624/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.816624/full

Similar Items