IDO1 Inhibitor RY103 Suppresses Trp-GCN2-Mediated Angiogenesis and Counters Immunosuppression in Glioblastoma

Glioma is characterized by strong immunosuppression and excessive angiogenesis. Based on existing reports, it can be speculated that the resistance to anti-angiogenic drug vascular endothelial growth factor A (VEGFA) antibody correlates to the induction of novel immune checkpoint indoleamine 2,3-dio...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Zikang Xing, Xuewen Li, Zhen Ning Tony He, Xin Fang, Heng Liang, Chunxiang Kuang, Aiying Li, Qing Yang
פורמט: Article
שפה:English
יצא לאור: MDPI AG 2024-06-01
סדרה:Pharmaceutics
נושאים:
גישה מקוונת:https://www.mdpi.com/1999-4923/16/7/870