Unraveling the roles of endoplasmic reticulum-associated degradation in metabolic disorders

Unraveling the roles of endoplasmic reticulum-associated degradation in metabolic disorders

Misfolded proteins retained in the endoplasmic reticulum cause many human diseases. ER-associated degradation (ERAD) is one of the protein quality and quantity control system located at ER, which is responsible for translocating the misfolded proteins or properly folded but excess proteins out of th...

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Bibliographic Details
Main Authors: Hui Luo, Qibin Jiao, Chuanbin Shen, Chenyi Shao, Jinyan Xie, Yue Chen, Xinglin Feng, Xingwei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Endocrinology
Subjects:
ERAD
quality control
quantity control
proteasomal degradation
metabolic disorders
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1123769/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1123769/full

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