Regulation of protein metabolism in cancer

Our recent studies determined molecular interactions between genes in the ubiquitin-proteasome pathways and cancer cell metabolism. Ubiquitin-specific peptidase 13 (USP13) specifically deubiquitinates and thus upregulates ATP citrate lyase and oxoglutarate dehydrogenase that drive ovarian cancer met...

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Bibliographic Details
Main Authors: Cecil Han, Xiongbin Lu, Deepak Nagrath
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1285384