Potential and Challenges for the Clinical Use of d-Serine As a Cognitive Enhancer

After 25 years of its discovery in the rat brain, d-serine is a recognized modulator of synaptic plasticity and cognitive processes through its actions on the NMDA-glutamate receptor. Importantly, cognitive impairment is a core feature of conditions, such as schizophrenia, Alzheimer’s disease, depre...

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Bibliographic Details
Main Authors: Gerson D. Guercio, Rogerio Panizzutti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fpsyt.2018.00014/full