Stability Study of Fosfomycin in Elastomeric Pumps at 4 °C and 34 °C: Technical Bases for a Continuous Infusion Use for Outpatient Parenteral Antibiotic Therapy

Stability Study of Fosfomycin in Elastomeric Pumps at 4 °C and 34 °C: Technical Bases for a Continuous Infusion Use for Outpatient Parenteral Antibiotic Therapy

Background: Fosfomycin acts against aerobic Gram−/+ bacteria by blocking the synthesis of peptidoglycan. Its use has been currently re-evaluated for intravenous administration for the treatment of systemic infections by multidrug-resistant bacteria. Concentration-/time-dependent activity has been su...

Full description

Bibliographic Details
Main Authors: Alessandra Manca, Alice Palermiti, Jacopo Mula, Jessica Cusato, Domenico Maiese, Marco Simiele, Amedeo De Nicolò, Antonio D’Avolio
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceutics
Subjects:
Fosfomycin
UHPLC
stability
OPAT
bridge therapy
Online Access:https://www.mdpi.com/1999-4923/15/9/2347

Internet

https://www.mdpi.com/1999-4923/15/9/2347

Similar Items