Structure-guided product determination of the bacterial type II diterpene synthase Tpn2
Crystal structure elucidation of terpene synthases plays an important role to understand the sequence-structure-function relationships of this enzyme class. Here, the authors determine the crystal structure of bacterial terpene synthase Tpn2, probe the catalytic mechanism by structure-guided mutatio...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-022-00765-6 |