The “Yin and Yang” of Unfolded Protein Response in Cancer and Immunogenic Cell Death

The “Yin and Yang” of Unfolded Protein Response in Cancer and Immunogenic Cell Death

Physiological and pathological burdens that perturb endoplasmic reticulum homeostasis activate the unfolded protein response (UPR), a conserved cytosol-to-nucleus signaling pathway that aims to reinstate the vital biosynthetic and secretory capacity of the ER. Disrupted ER homeostasis, causing malad...

Full description

Bibliographic Details
Main Authors: Nicole Rufo, Yihan Yang, Steven De Vleeschouwer, Patrizia Agostinis
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
ER stress
UPR
inflammation
cancer
immunogenic cell death
ICD
Online Access:https://www.mdpi.com/2073-4409/11/18/2899

Internet

https://www.mdpi.com/2073-4409/11/18/2899

Similar Items