A novel BCR-ABL1 fusion gene with genetic heterogeneity indicates a good prognosis in a chronic myeloid leukemia case

A novel BCR-ABL1 fusion gene with genetic heterogeneity indicates a good prognosis in a chronic myeloid leukemia case

Abstract Background Chronic myelogenous leukemia (CML) is a pluripotent hematopoietic stem cell disorder caused by the fusion of the BCR and ABL1 genes. Quantitative RT-PCR (qRT-PCR) is a routinely performed screening technique to identify BCR-ABL1 fusion genes, but a limitation of this method is it...

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Bibliographic Details
Main Authors: Fen Zhou, Runming Jin, Yu Hu, Heng Mei
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Molecular Cytogenetics
Subjects:
CML
BCR-ABL1
NGS
SH3 domain
Genetic heterogeneity
Online Access:http://link.springer.com/article/10.1186/s13039-017-0322-8

Internet

http://link.springer.com/article/10.1186/s13039-017-0322-8

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