A novel function for fragile X mental retardation protein in translational activation.

A novel function for fragile X mental retardation protein in translational activation.

Fragile X syndrome, the most frequent form of inherited mental retardation, is due to the absence of Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein involved in several steps of RNA metabolism. To date, two RNA motifs have been found to mediate FMRP/RNA interaction, the G-quartet...

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Main Authors: Elias G Bechara, Marie Cecile Didiot, Mireille Melko, Laetitia Davidovic, Mounia Bensaid, Patrick Martin, Marie Castets, Philippe Pognonec, Edouard W Khandjian, Hervé Moine, Barbara Bardoni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2628407?pdf=render

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http://europepmc.org/articles/PMC2628407?pdf=render

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