Haplotype block partitioning as a tool for dimensionality reduction in SNP association studies

<p>Abstract</p> <p>Background</p> <p>Identification of disease-related genes in association studies is challenged by the large number of SNPs typed. To address the dilution of power caused by high dimensionality, and to generate results that are biologically interpretab...

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Bibliographic Details
Main Authors: Fallin Danièle M, Ruczinski Ingo, Pattaro Cristian, Parmigiani Giovanni
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/405