LATS1-Beclin1 mediates a non-canonical connection between the Hippo pathway and autophagy

Understanding the mechanisms of evasive resistance in cancer is of great importance to develop efficient therapies. Analyzing the molecular mechanisms underlying therapy resistance of hepatocellular carcinoma (HCC), we have discovered a kinase-activity independent role of LATS1 (large tumor suppress...

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Bibliographic Details
Main Authors: Fengyuan Tang, Gerhard Christofori
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2020.1757378