Myofibroblasts: Function, Formation, and Scope of Molecular Therapies for Skin Fibrosis

Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in pathophysiological processes. Myofibroblasts mediate wound contractions, but their persistent presence in tissues is central to driving fibrosis, making them attractive cell targets for the development of the...

Full description

Bibliographic Details
Main Authors: Yifan Tai, Emma L. Woods, Jordanna Dally, Deling Kong, Robert Steadman, Ryan Moseley, Adam C. Midgley
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/8/1095