Myofibroblasts: Function, Formation, and Scope of Molecular Therapies for Skin Fibrosis
Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in pathophysiological processes. Myofibroblasts mediate wound contractions, but their persistent presence in tissues is central to driving fibrosis, making them attractive cell targets for the development of the...
Main Authors: | Yifan Tai, Emma L. Woods, Jordanna Dally, Deling Kong, Robert Steadman, Ryan Moseley, Adam C. Midgley |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/8/1095 |
Similar Items
-
USP10 Targeted Self-Deliverable siRNA to Prevent Scarring in the Cornea
by: Edward F. Boumil, et al.
Published: (2020-09-01) -
Andrographolide Inhibits Corneal Fibroblast to Myofibroblast Differentiation <i>In Vitro</i>
by: Vanessa Rozo, et al.
Published: (2022-10-01) -
Tissue repair, contraction and the myofibroblast /
by: 184340 Chaponnier, Christine, et al.
Published: (2006) -
Myofibroblasts in oral health and odontogenic lesions
by: Srikanth Ramarao Prabakar, et al.
Published: (2016-01-01) -
Understanding the impact of fibroblast heterogeneity on skin fibrosis
by: Michelle F. Griffin, et al.
Published: (2020-06-01)