TNF-Related Apoptosis-Inducing Ligand: Non-Apoptotic Signalling

TNF-related apoptosis-inducing ligand (TRAIL or Apo2 or TNFSF10) belongs to the TNF superfamily. When bound to its agonistic receptors, TRAIL can induce apoptosis in tumour cells, while sparing healthy cells. Over the last three decades, this tumour selectivity has prompted many studies aiming at ev...

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Bibliographic Details
Main Authors: Abderrahmane Guerrache, Olivier Micheau
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/6/521