ETV2 regulating PHD2-HIF-1α axis controls metabolism reprogramming promotes vascularized bone regeneration

ETV2 regulating PHD2-HIF-1α axis controls metabolism reprogramming promotes vascularized bone regeneration

The synchronized development of mineralized bone and blood vessels is a fundamental requirement for successful bone tissue regeneration. Adequate energy production forms the cornerstone supporting new bone formation. ETS variant 2 (ETV2) has been identified as a transcription factor that promotes en...

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Bibliographic Details
Main Authors: HaoRan Du, Bang Li, Rui Yu, Xiaoxuan Lu, ChengLin Li, HuiHui Zhang, Fan Yang, RongQuan Zhao, WeiMin Bao, Xuan Yin, YuanYin Wang, Jian Zhou, Jianguang Xu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-07-01
Series:Bioactive Materials
Subjects:
Vascularized bone regeneration
ETV2
Hypoxia-inducible factor-1α
Metabolism reprogramming
Microsphere
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24000598

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http://www.sciencedirect.com/science/article/pii/S2452199X24000598

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