Discrepancies in tumor mutation burden reporting from sequential endobronchial ultrasound transbronchial needle aspiration samples within single lymph node stations - brief report

Discrepancies in tumor mutation burden reporting from sequential endobronchial ultrasound transbronchial needle aspiration samples within single lymph node stations - brief report

IntroductionTumour Mutation Burden (TMB) is a potential biomarker for immune cancer therapies. Here we investigated parameters that might affect TMB using duplicate cytology smears obtained from endobronchial ultrasound transbronchial needle aspiration (EBUS TBNA)-sampled malignant lymph nodes.Metho...

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Bibliographic Details
Main Authors: David Fielding, Andrew J. Dalley, Mahendra Singh, Lakshmy Nandakumar, Vanessa Lakis, Haarika Chittoory, David Fairbairn, Ann-Marie Patch, Stephen H. Kazakoff, Kaltin Ferguson, Farzad Bashirzadeh, Michael Bint, Carl Pahoff, Jung Hwa Son, Kimberley Ryan, Alan Hodgson, Sowmya Sharma, John V. Pearson, Nicola Waddell, Sunil R. Lakhani, Gunter Hartel, Peter T. Simpson, Katia Nones
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
endobronchial ultrasound-guided transbronchial needle aspiration (EBUS TBNA)
lung cancer
cytology
TSO500
molecular diagnostics
tumor mutation burden
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1259882/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1259882/full

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