Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability

Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability

Objective: Liver mitochondria adapt to high-calorie intake. We investigated how exercise alters the early compensatory response of mitochondria, thus preventing fatty liver disease as a long-term consequence of overnutrition. Methods: We compared the effects of a steatogenic high-energy diet (HED) f...

Full description

Bibliographic Details
Main Authors: Miriam Hoene, Lisa Kappler, Laxmikanth Kollipara, Chunxiu Hu, Martin Irmler, Daniel Bleher, Christoph Hoffmann, Johannes Beckers, Martin Hrabě de Angelis, Hans-Ulrich Häring, Andreas L. Birkenfeld, Andreas Peter, Albert Sickmann, Guowang Xu, Rainer Lehmann, Cora Weigert
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Metabolism
Subjects:
Exercise
Mitochondrial supercomplexes
Acetyl-CoA
MAFLD
Lipidomics
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821002064

Internet

http://www.sciencedirect.com/science/article/pii/S2212877821002064

Similar Items