Intranasal Insulin Delivery: Microparticle Formulations Consisting of <i>Aloe vera</i> Polysaccharides for Advanced Delivery across Excised Olfactory and Respiratory Nasal Epithelial Tissues

Intranasal Insulin Delivery: Microparticle Formulations Consisting of <i>Aloe vera</i> Polysaccharides for Advanced Delivery across Excised Olfactory and Respiratory Nasal Epithelial Tissues

<i>Aloe vera</i> gel and whole leaf materials, as well as polysaccharides, precipitated from the gel, have previously been shown to enhance macromolecular drug delivery across epithelial tissues. This study investigated the effectiveness of microparticle formulations prepared from <i&...

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Bibliographic Details
Main Authors: Cassandra Kirby-Smith, Jan Steenekamp, Dewald Steyn, Anja Haasbroek-Pheiffer, Hannlie Hamman, Josias Hamman
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Applied Sciences
Subjects:
<i>Aloe vera</i> polysaccharides
ex vivo permeation
insulin delivery
intranasal administration
microparticles
olfactory epithelium
Online Access:https://www.mdpi.com/2076-3417/13/8/4822

Internet

https://www.mdpi.com/2076-3417/13/8/4822

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