PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis

Abstract Many types of cancer cells, including colorectal cancer cells (CRC), can simultaneously enhance glycolysis and repress the mitochondrial tricarboxylic acid (TCA) cycle, which is called the Warburg effect. However, the detailed mechanisms of abnormal activation of the glycolysis pathway in c...

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Bibliographic Details
Main Authors: Hao Liu, Xintian Chen, Pengfei Wang, Miaolei Chen, Chuyin Deng, Xingyou Qian, Jin Bai, Zhongwei Li, Xiangyang Yu
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06544-6