Association of HLA-DPA1, HLA-DPB1, and HLA-DQB1 Alleles With the Long-Term and Booster Immune Responses of Young Adults Vaccinated Against the Hepatitis B Virus as Neonates

Association of HLA-DPA1, HLA-DPB1, and HLA-DQB1 Alleles With the Long-Term and Booster Immune Responses of Young Adults Vaccinated Against the Hepatitis B Virus as Neonates

The neonatal hepatitis B vaccination (HBVac) was implemented 35 years ago in Taiwan, but many vaccinees exhibit inadequate long-term vaccine-induced seroprotective hepatitis B surface antibody (anti-HBs) levels. We investigated the association of the human leukocyte antigen (HLA) alleles (DPA1, DPB1...

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Bibliographic Details
Main Authors: Wen-Chang Wang, Yu-Shiang Lin, Yin-Fan Chang, Chih-Ching Yeh, Chien-Tien Su, Jin-Shang Wu, Fu-Hsiung Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
hepatitis B vaccine
human leukocyte antigen
booster
HBV serology
immunogenic response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.710414/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.710414/full

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