Two Novel Peptide Toxins from the Spider <i>Cyriopagopus longipes</i> Inhibit Tetrodotoxin-Sensitive Sodium Channels

Sodium channels play a critical role in the generation and propagation of action potentials in excitable tissues, such as nerves, cardiac muscle, and skeletal muscle, and are the primary targets of toxins found in animal venoms. Here, two novel peptide toxins (Cl6a and Cl6b) were isolated from the v...

Full description

Bibliographic Details
Main Authors: Qingfeng Zhang, Yuxin Si, Li Yang, Li Wang, Shuijiao Peng, Yiming Chen, Minzhi Chen, Xi Zhou, Zhonghua Liu
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/9/529