Mdm2 induces mono-ubiquitination of FOXO4.

Mdm2 induces mono-ubiquitination of FOXO4.

The Forkhead box O (FOXO) class of transcription factors are involved in the regulation of several cellular responses including cell cycle progression and apoptosis. Furthermore, in model organisms FOXOs act as tumor suppressors and affect aging. Previously, we noted that FOXOs and p53 are remarkabl...

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Bibliographic Details
Main Authors: Arjan B Brenkman, Peter L J de Keizer, Niels J F van den Broek, A G Jochemsen, Boudewijn M Th Burgering
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2475507?pdf=render

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http://europepmc.org/articles/PMC2475507?pdf=render

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