Selection of the Optimal L-asparaginase II Against Acute Lymphoblastic Leukemia: An In Silico Approach
BackgroundL-asparaginase II (asnB), a periplasmic protein commercially extracted from E coli and Erwinia, is often used to treat acute lymphoblastic leukemia. L-asparaginase is an enzyme that converts L-asparagine to aspartic acid and ammonia. Cancer cells are dependent on as...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
JMIR Publications
2021-09-01
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Series: | JMIRx Med |
Online Access: | https://med.jmirx.org/2021/3/e29844 |