Selection of the Optimal L-asparaginase II Against Acute Lymphoblastic Leukemia: An In Silico Approach

BackgroundL-asparaginase II (asnB), a periplasmic protein commercially extracted from E coli and Erwinia, is often used to treat acute lymphoblastic leukemia. L-asparaginase is an enzyme that converts L-asparagine to aspartic acid and ammonia. Cancer cells are dependent on as...

Full description

Bibliographic Details
Main Authors: Adesh Baral, Ritesh Gorkhali, Amit Basnet, Shubham Koirala, Hitesh Kumar Bhattarai
Format: Article
Language:English
Published: JMIR Publications 2021-09-01
Series:JMIRx Med
Online Access:https://med.jmirx.org/2021/3/e29844