Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex

Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are widely expressed in neurons in the central nervous system. It has been documented that HCN channels regulate the intrinsic excitability of pyramidal cells in the medial prefrontal cortex (mPFC) of rodents. Here, we report that HC...

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Bibliographic Details
Main Authors: Wei Cai, Shu-Su Liu, Bao-Ming Li, Xue-Han Zhang
Format: Article
Language:English
Published: The Company of Biologists 2022-03-01
Series:Biology Open
Subjects:
gabaergic transmission
hcn channel
mpfc
rats
Online Access:http://bio.biologists.org/content/11/3/bio058840

Internet

http://bio.biologists.org/content/11/3/bio058840

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