Efficacy of Prosopilosidine from Prosopis glandulosa var. glandulosa against Cryptococcus neoformans Infection in a Murine Model

In this study, 2,3-dihydro-1H-indolizinium alkaloid-prosopilosidine (PPD), that was isolated from Prosopis glandulosa, was evaluated against C. neoformans in a murine model of cryptococcosis. In vitro and in vivo toxicity of indolizidines were also evaluated. Mice were infected via the tail vein wit...

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Bibliographic Details
Main Authors: Mohammad K. Ashfaq, Mohamed Sadek Abdel-Bakky, Mir Tahir Maqbool, Volodymyr Samoylenko, Aziz Abdur Rahman, Ilias Muhammad
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/7/1674