Impact of sex on antidepressant discontinuation in groups of similar cytochrome P450 phenotypes

Impact of sex on antidepressant discontinuation in groups of similar cytochrome P450 phenotypes

Introduction: Although there are studies assessing reasons for antidepressant discontinuation, little is known about the impact of sex differences or cytochrome P450 phenotypes. Our objective is to assess discontinuation rates between males and females and whether CYP450 phenotype influences discont...

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Bibliographic Details
Main Authors: Dylan L. Kosaski, PharmD, Kristin C. Cole, Jessica A. Wright, Razan M. El Melik, PharmD, Simon Kung, MD, Wayne T. Nicholson, MD, PharmD, Jonathan G. Leung, PharmD
Format: Article
Language:English
Published: American Association of Psychiatric Pharmacists 2023-12-01
Series:Mental Health Clinician
Subjects:
antidepressants
depression
drug interactions
pharmacogenomics
pharmacokinetics
cytochrome p450
sex
gender
Online Access:https://theijpt.org/doi/pdf/10.9740/mhc.2023.12.303

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https://theijpt.org/doi/pdf/10.9740/mhc.2023.12.303

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