In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector

In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector

Biological applications deriving from the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 site-specific nuclease system continue to impact and accelerate gene therapy strategies. Safe and effective in vivo co-delivery of the CRISPR/Cas9 system to target somatic cells is essen...

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Bibliographic Details
Main Authors: Reka Lorincz, Aluet Borrego Alvarez, Christopher J. Walkey, Samir A. Mendonça, Zhi Hong Lu, Alexa E. Martinez, Cecilia Ljungberg, Jason D. Heaney, William R. Lagor, David T. Curiel
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Targeted nonhuman adenoviral vector
Selective gene delivery
Gene editing of vascular endothelium
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015785

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http://www.sciencedirect.com/science/article/pii/S0753332222015785

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