Serum progranulin is not associated with rs5848 polymorphism in Korean patients with neurodegenerative diseases.

Low serum progranulin (PGRN) is known to be associated with granulin (GRN) gene mutation and T alleles of GRN rs5848 polymorphism. However, there have been only a few Asian studies exploring these. We investigated the serum PGRN levels, rs5848 genotypes, and their relations with cerebrospinal fluid...

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Main Authors: Na-Yeon Jung, Hyang-Sook Kim, Eun Soo Kim, Sumin Jeon, Myung Jun Lee, Kyoungjune Pak, Jae-Hyeok Lee, Young Min Lee, Kangyoon Lee, Jin-Hong Shin, Jun Kyeung Ko, Jae Meen Lee, Jin A Yoon, Chungsu Hwang, Kyung-Un Choi, Gi Yeong Huh, Young-Eun Kim, Eun-Joo Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0261007