Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion

Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion

Abstract Background Gliomas with FGFR3::TACC3 fusion mainly occur in adults, display pathological features of glioblastomas (GB) and are usually classified as glioblastoma, IDH-wildtype. However, cases demonstrating pathological features of low-grade glioma (LGG) lead to difficulties in classificati...

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Main Authors: Alice Métais, Arnault Tauziède-Espariat, Jeremy Garcia, Romain Appay, Emmanuelle Uro-Coste, David Meyronet, Claude-Alain Maurage, Fanny Vandenbos, Valérie Rigau, Dan Christian Chiforeanu, Johan Pallud, Suhan Senova, Raphaël Saffroy, Carole Colin, Myriam Edjlali, Pascale Varlet, Dominique Figarella-Branger, The Biopathology RENOCLIP-LOC network
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Acta Neuropathologica Communications
Subjects:
FGFR3:TACC3 fusion
DNA-methylation profiling
2021 WHO classification of CNS tumours
Glioblastoma
Pediatric low grade glioma
Online Access:https://doi.org/10.1186/s40478-023-01506-z

Internet

https://doi.org/10.1186/s40478-023-01506-z

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