Gene Expression Signatures Based on Variability can Robustly Predict Tumor Progression and Prognosis

Gene expression signatures are commonly used to create cancer prognosis and diagnosis methods, yet only a small number of them are successfully deployed in the clinic since many fail to replicate performance on subsequent validation. A primary reason for this lack of reproducibility is the fact that...

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Bibliographic Details
Main Authors: Wikum Dinalankara, Héctor Corrada Bravo
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S23862