Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells

The extensive crosstalk between the developing heart and lung is critical to their proper morphogenesis and maturation. However, there remains a lack of models that investigate the critical cardio-pulmonary mutual interaction during human embryogenesis. Here, we reported a novel stepwise strategy fo...

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Bibliographic Details
Main Authors: Wai Hoe Ng, Elizabeth K Johnston, Jun Jie Tan, Jacqueline M Bliley, Adam W Feinberg, Donna B Stolz, Ming Sun, Piyumi Wijesekara, Finn Hawkins, Darrell N Kotton, Xi Ren
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/67872