High viral suppression and detection of dolutegravir-resistance associated mutations in treatment-experienced Tanzanian adults living with HIV-1 in Dar es Salaam

Abstract To curb HIV infection rate in Tanzania, antiretroviral therapy (ART) has been scaled up since 2006, and in 2019, the country shifted to regimen including dolutegravir as a default first line. We assessed the success of ART and the contribution of HIV drug resistance (HIVDR) to unsuppressed...

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Bibliographic Details
Main Authors: George M. Bwire, Beatrice Godwin Aiko, Idda H. Mosha, Mary S. Kilapilo, Alli Mangara, Patrick Kazonda, Janeth P. Swai, Omary Swalehe, Michael R. Jordan, Jurgen Vercauteren, David Sando, David Temba, Amani Shao, Wilhellmuss Mauka, Catherine Decouttere, Nico Vandaele, Raphael Z. Sangeda, Japhet Killewo, Anne-Mieke Vandamme
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47795-1