Concise and Free-Metal Access to Lactone-Annelated Pyrrolo[2,1-<i>a</i>]isoquinoline Derivatives via a 1,2-Rearrangement Step

Concise and Free-Metal Access to Lactone-Annelated Pyrrolo[2,1-<i>a</i>]isoquinoline Derivatives via a 1,2-Rearrangement Step

Here, An efficient approach to obtaining previously unknown furo[2′,3′:2,3]pyrrolo[2,1-<i>a</i>]isoquinoline derivatives from readily available 1-R-1-ethynyl-2-vinylisoquinolines is described. The reaction features a simple procedure, occurs in hexaflouroisopropanol and does not require...

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Bibliographic Details
Main Authors: Arina Y. Obydennik, Alexander A. Titov, Anna V. Listratova, Tatiana N. Borisova, Victor B. Rybakov, Leonid G. Voskressensky, Alexey V. Varlamov
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
hexaflouroisopropanol
lactonic pyrrolo[2,1-<i>a</i>]isoquinolines
pyrido[2,1-<i>a</i>]isoquinolines
[1,2]-sigmatropic rearrangement
trifluoroethanol
Online Access:https://www.mdpi.com/1422-0067/25/2/1085

Internet

https://www.mdpi.com/1422-0067/25/2/1085

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