Prediction of Liver Weight Recovery by an Integrated Metabolomics and Machine Learning Approach After 2/3 Partial Hepatectomy

Prediction of Liver Weight Recovery by an Integrated Metabolomics and Machine Learning Approach After 2/3 Partial Hepatectomy

Liver has an ability to regenerate itself in mammals, whereas the mechanism has not been fully explained. Here we used a GC/MS-based metabolomic method to profile the dynamic endogenous metabolic change in the serum of C57BL/6J mice at different times after 2/3 partial hepatectomy (PHx), and nine ma...

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Bibliographic Details
Main Authors: Runbin Sun, Haokai Zhao, Shuzhen Huang, Ran Zhang, Zhenyao Lu, Sijia Li, Guangji Wang, Jiye Aa, Yuan Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
liver regeneration
partial hepatectomy
metabolomics
machine learning
GC/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.760474/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.760474/full

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