The Effect of Vaccine Type and SARS-CoV-2 Lineage on Commercial SARS-CoV-2 Serologic and Pseudotype Neutralization Assays in mRNA Vaccine Recipients

The Effect of Vaccine Type and SARS-CoV-2 Lineage on Commercial SARS-CoV-2 Serologic and Pseudotype Neutralization Assays in mRNA Vaccine Recipients

ABSTRACT The use of anti-spike (S) serologic assays as surrogate measurements of SARS-CoV-2 vaccine induced immunity will be an important clinical and epidemiological tool. The characteristics of a commercially available anti-S antibody assay (Roche Elecsys anti-SARS-CoV-2 S) were evaluated in a coh...

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Bibliographic Details
Main Authors: Nicole V. Tolan, Amy C. Sherman, Guohai Zhou, Katherine G. Nabel, Michaël Desjardins, Stacy Melanson, Sanjat Kanjilal, Serina Moheed, John Kupelian, Richard M. Kaufman, Edward T. Ryan, Regina C. LaRocque, John A. Branda, Anand S. Dighe, Jonathan Abraham, Lindsey R. Baden, Richelle C. Charles, Sarah E. Turbett
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
mRNA vaccines
immunogenicity
serology
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00211-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00211-22

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