ARTseq-FISH reveals position-dependent differences in gene expression of micropatterned mESCs

Abstract Differences in gene-expression profiles between individual cells can give rise to distinct cell fate decisions. Yet how localisation on a micropattern impacts initial changes in mRNA, protein, and phosphoprotein abundance remains unclear. To identify the effect of cellular position on gene...

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Bibliographic Details
Main Authors: Xinyu Hu, Bob van Sluijs, Óscar García-Blay, Yury Stepanov, Koen Rietrae, Wilhelm T. S. Huck, Maike M. K. Hansen
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-48107-5