Response to Brigatinib Targeted Therapy in Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 19 Deletion, T790M, and cis-C797S Triple Mutations: A Case Report

Response to Brigatinib Targeted Therapy in Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 19 Deletion, T790M, and cis-C797S Triple Mutations: A Case Report

Epidermal growth factor receptor (<i>EGFR</i>) triple mutations with exon 19 deletion (del19), T790M, and cis-C797S (del19/T790M/cis-C797S mutations) frequently occur in patients with non-small cell lung cancer (NSCLC), while progression to frontline <i>EGFR</i>-tyrosine kina...

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Bibliographic Details
Main Authors: Zi-Wei Chen, Gigin Lin, Hsuan-Jen Shih, Chiao-En Wu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
brigatinib
NSCLC
T790M-cis-C797S
osimertinib resistance
EGFR triple mutation
<i>EGFR</i>-tyrosine kinase inhibitors resistance
Online Access:https://www.mdpi.com/1422-0067/24/1/602

Internet

https://www.mdpi.com/1422-0067/24/1/602

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