Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis
T cells express specific T cell receptors (TCR) to recognise antigens and initiate adaptive immune responses. Here the authors show, in a mouse model of autoimmune encephalomyelitis, that memory-like CD4 T cells expressing unrelated TCR can also infiltrate the spinal cord and contribute to autoimmun...
| Autores principales: | , , , , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
Nature Portfolio
2019-02-01
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| Colección: | Nature Communications |
| Acceso en línea: | https://doi.org/10.1038/s41467-019-08482-w |