A quest for cytosolic sequons and their functions

Abstract Evolution shapes protein sequences for their functions. Here, we studied the moonlighting functions of the N-linked sequon NXS/T, where X is not P, in human nucleocytosolic proteins. By comparing membrane and secreted proteins in which sequons are well known for N-glycosylation, we discover...

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Bibliographic Details
Main Authors: Manthan Desai, Syed Rafid Chowdhury, Bingyun Sun
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-57334-1