Diagnostic rate of germline pathogenic variants in pancreatic ductal adenocarcinoma patients using whole genome sequencing

Diagnostic rate of germline pathogenic variants in pancreatic ductal adenocarcinoma patients using whole genome sequencing

Identification of germline pathogenic variants in cancer patients is critical for treatment planning, genetic counseling, and health policymaking. However, previous estimates of the prevalence of germline etiology of pancreatic ductal adenocarcinoma (PDAC) were biased because they were based only on...

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Bibliographic Details
Main Authors: An-Ko Chung, Ro-Ting Lin, Chun-Chieh Yeh, Chi-Ying Yang, Chang-Jiun Wu, Pei-Lung Chen, Jaw-Town Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Genetics
Subjects:
pancreatic ductal adenocarcinoma (PADC)
whole genome sequencing (WGS)
germline genetic testing
structural variant (SV)
cancer genetic
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1172365/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1172365/full

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