Gut microbial signatures are associated with Lynch syndrome (LS) and cancer history in Druze communities in Israel

Abstract Lynch syndrome (LS) is a hereditary cancer syndrome caused by autosomal dominant mutations, with high probability of early onset for several cancers, mainly colorectal cancer (CRC). The gut microbiome was shown to be influenced by host genetics and to be altered during cancer development. T...

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Bibliographic Details
Main Authors: Rawi Naddaf, Shaqed Carasso, Gili Reznick-Levi, Erez Hasnis, Amalfi Qarawani, Itay Maza, Tal Gefen, Elizabeth Emily Half, Naama Geva-Zatorsky
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47723-3