Methylation and transcriptomic expression profiles of HUVEC in the oxygen and glucose deprivation model and its clinical implications in AMI patients

Methylation and transcriptomic expression profiles of HUVEC in the oxygen and glucose deprivation model and its clinical implications in AMI patients

The obstructed coronary artery undergoes a series of pathological changes due to ischemic-hypoxic shocks during acute myocardial infarction (AMI). However, the altered DNA methylation levels in endothelial cells under these conditions and their implication for the etiopathology of AMI have not been...

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Bibliographic Details
Main Authors: Yuning Tang, Yongxiang Wang, Shengxiang Wang, Runqing Wang, Jin Xu, Yu Peng, Liqiong Ding, Jing Zhao, Gang Zhou, Shougang Sun, Zheng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Genetics
Subjects:
DNA methylation
oxygen-glucose deprivation
acute myocardial infarction
mRNA sequence
brain-derived neurotrophic factor
tumor necrosis factor superfamily member 10
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1293393/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1293393/full

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